In the MI-DNA DISC project, in Work Package 1 AIT plays the role of scientific and operational coordinator and it is also responsible for Work Package 4, dedicated to the hardware development: here, AIT leads the development activities of the hardware components for the writing and storing cartridges for the short-, medium-, and long-term storage of the DNA-based information. Moreover, AIT is in charge of coordinating the DigNA portfolio activities within the project consortium, reporting to the EIC about the advancements in the cooperation between MI-DNA DISC and the rest of the portfolio of DNA-storage projects.
In the project, the Faculty of Science of the University of Zagreb is responsible for Work Package 5, dedicated to the in silico and in vitro evaluation of DNA nanostructure stability, the evaluation and optimisation of the writing cartridge and the evaluation and optimisation of the storing and editing cartridge.
The Technical University of Munich (TUM) is responsible for Work Package 3, dedicated to synthetic biology activities. Specifically, TUM is involved in the selection of optimal bacterial species, leads the development of photoswitches for oligonucleotide synthesis, of photoswitches for DNA uptake and release and develops the synthesis protocol using in vivo generated oligonucleotides.
In the MI-DNA DISC project, Eko Refugium is responsible for Work Package 2, dedicated to the development of all software tools required for the realisation of the writing and storing cartridges. This includes the development of functions for (i) binarization, (ii) DNA encoding, (iii) decoding, (iv) error correction and (v) the writing and storing cartridge control software. Furthermore, Eko Refugium is contributing to the development and prototyping of hardware components.
Day One is responsible for Work Package 6, which is dedicated to dissemination, communication, exploitation and IP protection. Activities include design thinking of new potential products resulting from research activities, IP management and the development of an exploitation plan and of a coherent communication and dissemination plan. Day One is also involved in Work Package 7, aimed at supporting the EIC Pathfinder challenge ‘DNA-based digital data storage’, of which leads Workgroup 2, focused on outreach and public engagement.